The biobank is an Institutional Review Board approved, federally regulated repository of human blood samples and data localized to disease states over a duration of time. The biobank allows for a comprehensive network of clinical, demographic, genetic, organ specific data, and more to analyze in various applied mathematical models to determine associations for disease interventions.
TPIRC uses precision medicine and data analytics to drive both treatment and research in orphan diseases. TPIRC's primary focus areas are food allergies, cystic fibrosis, bronchiectasis, airway inflammatory disorders, and immunodeficiency.
The TPIRC Biobank was created as a research resource that includes bio-specimens and clinical data collected longitudinally from TPIRC patients. TPIRC researchers, their collaborators, and other approved investigators use the biobank to support studies in food allergy, cystic fibrosis, bronchiectasis, airway inflammatory disorders, immunodeficiency and other clinical treatment and research areas aligned with TPIRC's work. While our clinical research is often focused upon the N of 1 model, the biobank complements that work by facilitating related research that requires larger data sets.
This research helps in many ways, including defining the mechanisms at play in Southern California Food Allergy Institute's Tolerance Induction Program (TIP). This leads to the discovery of new biomarkers that can help our patients today and in the future.